Search on: RIBONUCLEASE H, HUMAN IMMUNODEFICIENCY VIRUS 
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Descriptor English:   Ribonuclease H, Human Immunodeficiency Virus 
Descriptor Spanish:   Ribonucleasa H del Virus de la Inmunodeficiencia Humana 
Descriptor Portuguese:   Ribonuclease H do Vírus da Imunodeficiência Humana 
Tree Number:   D08.811.277.352.355.350.700.500
D08.811.277.352.700.350.700.500
D12.776.964.775.375.545.875.500
D12.776.964.775.562.875.875.500
D12.776.964.970.600.850.375.545.875.500
D12.776.964.970.600.850.375.750.187.500
Definition English:   A ribonuclease activity that is a component of the HIV REVERSE TRANSCRIPTASE. It removes the RNA strand of the RNA-DNA heteroduplex produced by reverse transcription. Once the RNA moiety is removed a double stranded DNA copy of the HIV RNA can be synthesized. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52675 
Unique Identifier:   D054309 

Occurrence in VHL:
 

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